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- Refrigerants
- Second-generation
- Third-generation
- Blended refrigerant
- Fourth-generation
- UV Series
- UV absorber
- Light stabilizers
- Melanin



Shandong Do Sender Chemicals Co.,Ltd.
- Refrigerants
- Second-generation
- Third-generation
- Blended refrigerant
- Fourth-generation
- UV Series
- UV absorber
- Light stabilizers
- Melanin
- …
- Refrigerants
- Second-generation
- Third-generation
- Blended refrigerant
- Fourth-generation
- UV Series
- UV absorber
- Light stabilizers
- Melanin

R410A
Pentafluoroethane/Difluoromethane (R410A)
CAS No.:354-33-6/75-10-5 UN No.: 3163 CLASS No.: 2.2 Molecular formula: CF3CHF2/CH2F2
R410A is a mixture of R32 and R125, which can be used to replace R22.

R410A
R410A is a zeotropic blend of difluoromethane (R32, CAS 75-10-5) and pentafluoroethane (R125, CAS 354-33-6) in a 50%/50% mass fraction. It's a hydrofluorocarbon (HFC) refrigerant with zero ozone depletion potential (ODP) commonly used as a replacement for R22 in air conditioning applications.
Applications
Residential Air Conditioning
Primary refrigerant in split-system and packaged AC units
Commercial Air Conditioning
Applied in rooftop units, VRF systems, and chillers
Heat Pumps
Both air-source and water-source heat pump systems
Transport Refrigeration
Some mobile air conditioning applications
Dehumidificationa Systems
Industrial and commercial dehumidifiers
Physical & Chemical Properties
Physical Properties
Boiling Point (1 atm): -51.5°C (-60.7°F)
Critical Temperature: 71.4°C (160.5°F)
Critical Pressure: 4.81 MPa (698 psia)
Liquid Density (25°C): ~1,060 kg/m³
Vapor Density (air=1): ~3.0
ODP (Ozone Depletion): 0
GWP (Global Warming): 2,088 (IPCC AR5)
Flammability: A1 - Non-flammable (R32 flammability fully suppressed by R125)
Thermodynamic & Performance Characteristics
Glide: Negligible (<0.1°C) - Behaves almost like a single-component refrigerant, simplifying system design and charging.
Operating Pressure: ~50-60% higher than R22. Requires specifically designed components (compressors, heat exchangers, piping).
Volumetric Cooling Capacity: ~40-50% higher than R22. Allows for more compact system designs.
Coefficient of Performance (COP): Generally 5-8% higher than R22 in optimized systems.
Discharge Temperature: Similar to or slightly lower than R22, good for compressor reliability.
Heat Transfer: Superior heat transfer coefficients compared to R22.
Material Compatibility & Handling
Lubricant: Polyol Ester (POE) Oil exclusively. Not miscible with mineral or alkylbenzene oils.
Seal Materials: Compatible with HNBR, EPDM, Neoprene. Avoid natural rubber.
Metals: Compatible with copper, brass, steel, aluminum.
Charging Method: Can be charged as liquid or vapor with minimal composition shift due to near-azeotropic nature.
System Design: Must use components rated for higher pressure (typically ≥400 psi working pressure).
Packaging, Storage & Transportation
Packaging
Disposable Cylinders: 10lb, 25lb, 50lb
Returnable Cylinders: 100lb, 500lb, 1000lb
ISO Tanks: 20,000lb+
Storage
Store in a cool, dry, well-ventilated area away from direct sunlight
Keep away from heat sources, sparks, and open flames
Storage temperature should not exceed 125°F (52°C)
Cylinders should be stored upright and secured to prevent tipping
Keep valve protection caps on when not in use
Transportation
DOT/UN classified as UN1078, Fluorinated gases, n.o.s. (R410A)
Proper shipping name: Refrigerant gas R410A
Transport in upright position with valves closed and protected
Vehicles should be well-ventilated during transport
Comply with local and international regulations (EPA, F-Gas, etc.)
FAQ
What is the chemical composition of R410A refrigerant?
What are the CAS numbers for R410A components?
Is R410A being phased out due to environmental regulations?
What is the operating pressure of R410A compared to R22?
Can R410A be used as a drop-in replacement for R22?
What is the temperature glide of R410A refrigerant?
What type of oil is compatible with R410A systems?
What is the global warming potential (GWP) of R410A?
Is R410A flammable or toxic?
What are common applications for R410A refrigerant?
What are the storage requirements for R410A cylinders?
How should R410A cylinders be transported safely?
What are the environmental benefits of R410A compared to R22?
What safety precautions are needed when handling R410A?
Can R410A be mixed with other refrigerants?
What is the boiling point of R410A at atmospheric pressure?
What are the common cylinder sizes for R410A?
How does R410A compare to R32 refrigerant?
What recovery requirements apply to R410A?
What is the critical temperature and pressure of R410A?
How should leaks in R410A systems be detected?
What are the common alternatives to R410A?
Refrigerants
Second Refrigerant
R22
Third Generation
R32
R23
HFC-143A
R134A
HFC-125
R152A
Blended Refrigerant
R404A
R407C
R410A
R507A
Fourth Generation
R1234YF
UV Series
UV absorber
UV-1164
BP-2
UV-1
UV-123
UV-327
UV-P
UV-329
UV-1130
Light satabilizers
UV-292
UV-770
Melanin
2-Anilino-6-(dibutylamino)-3-me
Other chemicals
2-Hydroxy-2methylpropiophenone
1,3-benzothiazol-2-ylsulfanylme
4-Chloro-3,5-dimethylphenol (CA
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Sales Office Address:No. 66, Zhongrun Avenue, Zhangdian District, Zibo City, Shandong Province,China.
Manufacture Facility: Fine Chemical Industry Park, Zhangdian District, Zibo City, Shandong Province,China.
