• Product Overview: 4-Chloro-3,5-dimethylphenol (CAS 88-04-0)

    4-Chloro-3,5-dimethylphenol (commonly known as Chloroxylenol or PCMX) is a broad-spectrum antimicrobial agent belonging to the halophenol class. It appears as a white to off-white crystalline powder with a characteristic phenolic odor . It is the active ingredient in antiseptic formulations like Dettol and is included in the WHO Model List of Essential Medicines . PCMX is effective against a wide range of Gram-positive and Gram-negative bacteria, fungi, and molds, making it one of the most widely used antiseptics in pharmaceutical, personal care, and industrial applications

    Property Typical Value

    Appearance (23°C) Red to brown liquid with pungent odor

    Purity (HPLC) ≥95% (technical grade)

    Molecular Formula C₉H₆N₂S₃

    Molecular Weight 238.34 – 238.36 g/mol

    Density (25°C) 1.05 (c = 0.30)

    Flash Point (open cup) 66°C

    Log Kow (Octanol-Water) 3.30 (experimental)

    Solubility & Compatibility Profile

    Parameter Details

    IUPAC Name 1,3-benzothiazol-2-ylsulfanylmethyl thiocyanate

    Synonyms TCMTB, 2-(Thiocyanomethylthio)benzothiazole, Busan,

    Benthiazole, Alentisan, Superdavloxan, Sancelant TMB

    EINECS/EC Number 244-445-0

    PubChem CID30692

    MDL Number MFCD00072503

    UN Number 3026 (for certain formulations)

    InChI Key TUBQDCKAWGHZPF-UHFFFAOYSA-N

  • Performance Advantages
    Broad-Spectrum Activity: Effective against fungi, bacteria, and algae across multiple industrial applications
    Industrial Versatility: Used in leather processing, water treatment, pulp/paper, wood preservation, and paints
    Microbial Control: Disrupts microbial cell function, preventing material degradation and biofouling
    Solubility: Soluble in most organic solvents, facilitating formulation in various industrial products
    EPA Registered: Listed as an active ingredient in pesticide formulations and regulated under FIFRA
    TCMTB is a versatile industrial biocide used across multiple sectors for microbial control and material preservation :
    Leather processing (fungicide)
    Water treatment / cooling towers
    Pulp & paper mills (slimicide)
    Wood preservation Paints & coatings preservative
    Textile processing Carpet / wallpaper adhesives
    Seed treatment (cereals, cotton, corn)
    Marine anti-fouling / zebra mussel control
    Industrial wastewater systems
    Leather Industry

    TCMTB is widely used as a fungicide in leather processing to prevent microbial degradation during tanning and storage. It protects wet-blue and finished leather from fungal attack, ensuring product quality and longevity Studies confirm its effectiveness as a fungicide on leather

    Water Treatment & Pulp/Paper

    In industrial water systems, cooling towers, and pulp/paper mills, TCMTB serves as an effective slimicide and bactericide, controlling slime-forming bacteria and fungi that cause blockages and degradation [citation:3][citation:7]. It is used as a preservative and slimicide in paper production

    Wood Preservation & Agriculture
    TCMTB is used as a wood preservative, protecting lumber from fungal decay and insect damage [citation:3][citation:9]. In agriculture, it is applied as a contact fungicide for seed treatment (barley, cotton, corn, rice, sorghum, sugar beets, wheat) to prevent seed-borne diseases
    Standard Packaging
    Various container sizes available depending on concentration and formulation (technical grades 30%, 60%, 80%)
    Laboratory/R&D sizes: 25mg, 100mg, 250mg, 1g (for research use only) .
    Industrial drums: Typically 200kg or custom packaging for bulk shipments.
    Storage Conditions
    Store in a cool, dry, well-ventilated area away from direct sunlight and heat sources
    Long-term storage: Recommended at -20°C to maintain stability
    Keep containers tightly sealed; protect from moisture and incompatible materials.
    Avoid storage near strong oxidizing agents, strong acids, or bases.
    Shelf life: When stored properly, ≥24 months from manufacture date (typical).
    Shelf life: Minimum 24 months from manufacture date when stored properly under recommended conditions.
    Transport Information
    IMO/IMDG Not dangerous goods
    IATA Not restricted
    ADR/RID Non-hazardous for transport
  • Frequently Asked Questions (FAQ)