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- Refrigerants
- Second-generation
- Third-generation
- Blended refrigerant
- Fourth-generation
- UV Series
- UV absorber
- Light stabilizers
- Melanin



Shandong Do Sender Chemicals Co.,Ltd.
- Refrigerants
- Second-generation
- Third-generation
- Blended refrigerant
- Fourth-generation
- UV Series
- UV absorber
- Light stabilizers
- Melanin
- …
- Refrigerants
- Second-generation
- Third-generation
- Blended refrigerant
- Fourth-generation
- UV Series
- UV absorber
- Light stabilizers
- Melanin

R22
Industrial Difluorochloromethane (R22)
CAS No.: 75-45-6 UN No.: 1018 CLASS No.: 2.2 Molecular formula: CHClF₂
It is used as a refrigerant and pesticide spray propellant, and also as a raw material for fire extinguishing agents and fluororesins.

R22
R22 (Chlorodifluoromethane), also known as HCFC-22, is a hydrochlorofluorocarbon (HCFC) refrigerant with CAS number 75-45-6. It has been widely used as a refrigerant in various air conditioning, refrigeration, and heat pump systems due to its favorable thermodynamic properties and non-flammability.
Applications
Residential Air Conditioning
Widely used in split-system and packaged air conditioners for homes and small buildings manufactured before 2010.
Commercial HVAC Systems
Applied in rooftop units, chillers, and commercial air conditioning systems for medium to large buildings.
Transport Refrigeration
Used in refrigerated trucks, trailers, and shipping containers for food and pharmaceutical transport.
Industrial Process Cooling
Employed in industrial chillers, cold storage facilities, and specialized process cooling applications.
Chemical Feedstock
Serves as a precursor in the production of fluoropolymers like PTFE (Teflon) and other fluorinated compounds.
Heat Pump Systems
Utilized in both air-source and ground-source heat pumps for heating and cooling applications.
Physical & Chemical Properties
Thermodynamic Properties
Boiling Point: -40.7°C (-41.3°F) at 1 atm
Freezing Point: -157.4°C (-251.3°F)
Critical Temperature: 96.0°C (204.8°F)
Critical Pressure: 4.99 MPa (49.2 atm)
Latent Heat of Vaporization: 233.9 kJ/kg at boiling point
Safety & Handling Properties
Flammability: Non-flammable
Autoignition Temperature: Not applicable (non-flammable)
Exposure Limits (OSHA PEL): 1000 ppm (8-hour TWA)
Vapor Density: 3.0 (air = 1)
Solubility in Water: 0.3% by weight at 25°C
Environmental Properties
Ozone Depletion Potential (ODP): 0.055 (relative to CFC-11 = 1)
Global Warming Potential (GWP): 1,810 (100-year, CO₂ = 1)
Atmospheric Lifetime: 11.9 years
Hydroxyl Reactivity: 0.02 (relative to methane)
Packaging, Storage & Transportation
Cylinder Sizes
Available in various cylinder sizes: 10 lb, 25 lb, 30 lb, and 50 lb disposable cylinders. Also available in 100 lb, 500 lb, and 1,000 lb recovery cylinders for reclaimed R22.
Bulk Containers
For large-scale users: 1-ton cylinders and ISO tank containers for industrial applications and reclamation facilities.
Storage Conditions
Store in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep away from open flames and ignition sources. Cylinder temperature should not exceed 52°C (125°F).。
Transportation
Classified as UN 1018, Chlorodifluoromethane (R22). Transport as a non-flammable gas. Cylinders must be secured upright during transport with valve protection caps in place.
FAQ
What is R22 refrigerant and what is its CAS number?
Is R22 (CAS 75-45-6) still being produced?
What are the environmental concerns with R22 (CAS 75-45-6)?
What is the chemical formula of R22 (CAS 75-45-6)?
What are common alternatives to R22 (CAS 75-45-6)?
What is the boiling point of R22 (CAS 75-45-6)?
Is R22 (CAS 75-45-6) flammable?
What safety precautions should be taken when handling R22 (CAS 75-45-6)?
Can R22 (CAS 75-45-6) be mixed with other refrigerants?
What is the molecular weight of R22 (CAS 75-45-6)?
How is R22 (CAS 75-45-6) typically packaged for distribution?
What are the primary applications of R22 (CAS 75-45-6)?
What is the critical temperature of R22 (CAS 75-45-6)?
What are the health effects of exposure to R22 (CAS 75-45-6)?
What is the vapor density of R22 (CAS 75-45-6) compared to air?
How should R22 (CAS 75-45-6) cylinders be stored?
What is the solubility of R22 (CAS 75-45-6) in water?
What are the disposal requirements for R22 (CAS 75-45-6)?
What is the atmospheric lifetime of R22 (CAS 75-45-6)?
What certifications are required to handle R22 (CAS 75-45-6)?
Refrigerants
Second Refrigerant
R22
Third Generation
R32
R23
HFC-143A
R134A
HFC-125
R152A
Blended Refrigerant
R404A
R407C
R410A
R507A
Fourth Generation
R1234YF
UV Series
UV absorber
UV-1164
BP-2
UV-1
UV-123
UV-327
UV-P
UV-329
UV-1130
Light satabilizers
UV-292
UV-770
Melanin
2-Anilino-6-(dibutylamino)-3-me
Other chemicals
2-Hydroxy-2methylpropiophenone
1,3-benzothiazol-2-ylsulfanylme
4-Chloro-3,5-dimethylphenol (CA
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Manufacture Facility: Fine Chemical Industry Park, Zhangdian District, Zibo City, Shandong Province,China.
