



Shandong Do Sender Chemicals Co.,Ltd.
- Refrigerants
- Second-generation
- Third-generation
- Blended refrigerant
- Fourth-generation
- UV Series
- UV absorber
- Light stabilizers
- Melanin
- …
- Refrigerants
- Second-generation
- Third-generation
- Blended refrigerant
- Fourth-generation
- UV Series
- UV absorber
- Light stabilizers
- Melanin



Shandong Do Sender Chemicals Co.,Ltd.
- Refrigerants
- Second-generation
- Third-generation
- Blended refrigerant
- Fourth-generation
- UV Series
- UV absorber
- Light stabilizers
- Melanin
- …
- Refrigerants
- Second-generation
- Third-generation
- Blended refrigerant
- Fourth-generation
- UV Series
- UV absorber
- Light stabilizers
- Melanin

HFC-143A/R143A
1,1,1-Trifluoroethane (HFC-143a)
CAS No.: 420-46-2 UN No.: 2035 CLASS No.: 2.1 Molecular formula: CF₃CH₃
It is mainly used as a raw material for special refrigerants or mixed refrigerants such as R404, R408, R507, etc.

R143A
R143a (trifluoroethane) is a flammable (A2), high-GWP (4470) refrigerant. It is not used alone but as a key component in commercial blends like R404A/R507A to provide capacity and stability. Due to its severe environmental impact, it is being phased out globally.
Applications
Refrigerant Blends Component
Primary component in R-404A, R-407A, R-407B, R-407C, R-407D, R-407E, and R-507A blends used in commercial refrigeration systems.
Centrifugal Chillers
Used as a component in refrigerant blends for centrifugal chillers in large commercial and industrial air conditioning systems.
Medium-Temperature Refrigeration
Applied in supermarket display cases, walk-in coolers, and food processing refrigeration systems.
Industrial Process Cooling
Used in industrial chillers for plastics manufacturing, pharmaceutical production, and chemical processing.
Transport Refrigeration
Component in refrigerant blends for truck, trailer, and shipping container refrigeration units.
Propellant Formulations
Used in specialized aerosol propellant applications where specific thermodynamic properties are required.
Physical & Chemical Properties
Physical Properties
Molecular Weight: 84.04 g/mol
Boiling Point (1 atm): -47.2°C(-53.0°F)
Freezing Point: -111.3°C (-168.3°F)
Critical Temperature: 73.1°C(163.6°F)
Critical Pressure: 3.76 MPa (545 psia)
Liquid Density (25°C): ~950 kg/m³
Vapor Density (air=1): 2.9
Specific Heat (Liquid, 25°C): ~1.45 kJ/(kg·K)
Chemical & Safety Properties
Flammability: Class A2 - Flammable (Not A2L). Higher flammability than R32.
Lower Flammability Limit (LFL): 6.0% by volume in air (More flammable than R32's 14.4%)
Upper Flammability Limit (UFL): 11.4% by volume
Auto-Ignition Temperature: ~705°C (1,300°F)
ODP (Ozone Depletion): 0
GWP (Global Warming): 4470 (IPCC AR5) - Extremely High
Atmospheric Lifetime: ~52 years
Toxicity: Class A (Low toxicity at normal exposure)
Stability: Stable under normal conditions. Decomposes in flames to toxic HF/COF₂.
Thermodynamic & Application Notes
Performance: Used primarily as a component in blends (e.g., R404A, R407C, R507A) to provide capacity and reduce flammability of other components like R32.
Glide: Used in zeotropic blends; rarely used as a pure refrigerant.
Oil Compatibility: Requires Polyol Ester (POE) oils.
Material Compatibility: Compatible with standard metals; use HNBR/EPDM elastomers.
Packaging, Storage & Transportation
Cylinder Sizes
Available in 10 lb, 25 lb, 30 lb, 50 lb disposable cylinders. Also offered in 100 lb, 500 lb, 1,000 lb recovery cylinders for reclaimed R143a.
Bulk Containers
For large-scale use: 1-ton cylinders and ISO tank containers are available for industrial applications and reclamation facilities.
Storage Conditions
Store in a cool, dry, well-ventilated area away from direct sunlight, heat sources, open flames, and ignition sources. Cylinder temperature must not exceed 52°C (125°F). Keep cylinders upright and secured, and avoid mixing with oxidizers, corrosive substances, or other refrigerants.
Transportation
Classified as UN 3252, 1,1,1-Trifluoroethane (R143a), a Class 2.1 Flammable Gas. Transport using dedicated hazardous goods vehicles with fire-fighting equipment and anti-leakage measures. Secure cylinders upright with valve protection caps in place; avoid high-temperature exposure and direct sunlight. Drivers and handlers must hold hazardous goods operation certifications.
FAQ
What is R143A (CAS NO. 420-46-2)?
What are the primary applications of R143A with CAS NO. 420-46-2?
What is the global warming potential (GWP) of R143A (CAS 420-46-2)?
Is R143A (CAS 420-46-2) flammable?
What is the ozone depletion potential (ODP) of R143A CAS 420-46-2?
What are the critical temperature and pressure of R143A CAS 420-46-2?
How does R143A (CAS 420-46-2) compare to R134a?
What safety precautions are necessary when handling R143A CAS 420-46-2?
What are the environmental regulations affecting R143A CAS 420-46-2?
Can R143A CAS 420-46-2 be used as a direct replacement for R22?
What is the vapor pressure of R143A CAS 420-46-2 at 25°C?
What lubricants are compatible with R143A CAS 420-46-2?
What is the autoignition temperature of R143A CAS 420-46-2?
How is R143A CAS 420-46-2 manufactured?
What are the alternatives to R143A CAS 420-46-2 with lower GWP?
What is the liquid density of R143A CAS 420-46-2 at 25°C?
Can R143A CAS 420-46-2 be mixed with other refrigerants?
What are the recovery and recycling requirements for R143A CAS 420-46-2?
What is the atmospheric lifetime of R143A CAS 420-46-2?
How should leaks of R143A CAS 420-46-2 be detected?
Refrigerants
Second Refrigerant
R22
Third Generation
R32
R23
HFC-143A
R134A
HFC-125
R152A
Blended Refrigerant
R404A
R407C
R410A
R507A
Fourth Generation
R1234YF
UV Series
UV absorber
UV-1164
BP-2
UV-1
UV-123
UV-327
UV-P
UV-329
UV-1130
Light satabilizers
UV-292
UV-770
Melanin
2-Anilino-6-(dibutylamino)-3-me
Other chemicals
2-Hydroxy-2methylpropiophenone
1,3-benzothiazol-2-ylsulfanylme
4-Chloro-3,5-dimethylphenol (CA
About
Home
News
Contact
© 2025 Shandong Do Sender Chemicals Co.,Ltd. All rights reserved.
Sales Office Address:No. 66, Zhongrun Avenue, Zhangdian District, Zibo City, Shandong Province,China.
Manufacture Facility: Fine Chemical Industry Park, Zhangdian District, Zibo City, Shandong Province,China.
